Plug & Play Directed Evolution of Proteins with Gradient-based Discrete
MCMC

Plug & Play Directed Evolution of Proteins with Gradient-based Discrete MCMC

20 December 2022

Aidan Perreault

David J. Biagioni

Peter C. St. John

Papers citing "Plug & Play Directed Evolution of Proteins with Gradient-based Discrete MCMC"

13 / 13 papers shown

Title
Unlocking Guidance for Discrete State-Space Diffusion and Flow Models Hunter Nisonoff Junhao Xiong Stephan Allenspach Jennifer Listgarten 91 37 0 03 Jun 2024
RITA: a Study on Scaling Up Generative Protein Sequence Models Daniel Hesslow Niccoló Zanichelli Pascal Notin Iacopo Poli D. Marks 35 95 0 11 May 2022
COLD Decoding: Energy-based Constrained Text Generation with Langevin Dynamics Lianhui Qin Sean Welleck Daniel Khashabi Yejin Choi AI4CE 74 147 0 23 Feb 2022
Design-Bench: Benchmarks for Data-Driven Offline Model-Based Optimization Brandon Trabucco Xinyang Geng Aviral Kumar Sergey Levine OffRL 50 97 0 17 Feb 2022
Unifying Likelihood-free Inference with Black-box Optimization and Beyond Dinghuai Zhang Jie Fu Yoshua Bengio Aaron Courville 54 14 0 06 Oct 2021
Deep Extrapolation for Attribute-Enhanced Generation Alvin Chan Ali Madani Ben Krause Nikhil Naik 54 26 0 07 Jul 2021
Protein sequence design with deep generative models Zachary Wu Kadina E. Johnston F. Arnold Kevin Kaichuang Yang 41 138 0 09 Apr 2021
Model Inversion Networks for Model-Based Optimization Aviral Kumar Sergey Levine OffRL 71 95 0 31 Dec 2019
Plug and Play Language Models: A Simple Approach to Controlled Text Generation Sumanth Dathathri Andrea Madotto Janice Lan Jane Hung Eric Frank Piero Molino J. Yosinski Rosanne Liu KELM 98 957 0 04 Dec 2019
Conditioning by adaptive sampling for robust design David H. Brookes Hahnbeom Park Jennifer Listgarten 49 197 0 29 Jan 2019
The Concrete Distribution: A Continuous Relaxation of Discrete Random Variables Chris J. Maddison A. Mnih Yee Whye Teh BDL 108 2,523 0 02 Nov 2016
Automatic chemical design using a data-driven continuous representation of molecules Rafael Gómez-Bombarelli Jennifer N. Wei David Duvenaud José Miguel Hernández-Lobato Benjamín Sánchez-Lengeling Dennis Sheberla J. Aguilera-Iparraguirre Timothy D. Hirzel Ryan P. Adams Alán Aspuru-Guzik 3DV 123 2,911 0 07 Oct 2016
Intriguing properties of neural networks Christian Szegedy Wojciech Zaremba Ilya Sutskever Joan Bruna D. Erhan Ian Goodfellow Rob Fergus AAML 166 14,831 1 21 Dec 2013