Taming Stable Diffusion for Computed Tomography Blind Super-Resolution

High-resolution computed tomography (CT) imaging is essential for medical diagnosis but requires increased radiation exposure, creating a critical trade-off between image quality and patient safety. While deep learning methods have shown promise in CT super-resolution, they face challenges with complex degradations and limited medical training data. Meanwhile, large-scale pre-trained diffusion models, particularly Stable Diffusion, have demonstrated remarkable capabilities in synthesizing fine details across various vision tasks. Motivated by this, we propose a novel framework that adapts Stable Diffusion for CT blind super-resolution. We employ a practical degradation model to synthesize realistic low-quality images and leverage a pre-trained vision-language model to generate corresponding descriptions. Subsequently, we perform super-resolution using Stable Diffusion with a specialized controlling strategy, conditioned on both low-resolution inputs and the generated text descriptions. Extensive experiments show that our method outperforms existing approaches, demonstrating its potential for achieving high-quality CT imaging at reduced radiation doses. Our code will be made publicly available.

@article{li2025_2506.11496,
  title={ Taming Stable Diffusion for Computed Tomography Blind Super-Resolution },
  author={ Chunlei Li and Yilei Shi and Haoxi Hu and Jingliang Hu and Xiao Xiang Zhu and Lichao Mou },
  journal={arXiv preprint arXiv:2506.11496},
  year={ 2025 }
}