The Intelligent System of Emergent Knowledge (ISEK) establishes a decentralized network where human and artificial intelligence agents collaborate as peers, forming a self-organizing cognitive ecosystem. Built on Web3 infrastructure, ISEK combines three fundamental principles: (1) a decentralized multi-agent architecture resistant to censorship, (2) symbiotic AI-human collaboration with equal participation rights, and (3) resilient self-adaptation through distributed consensus mechanisms.The system implements an innovative coordination protocol featuring a six-phase workflow (Publish, Discover, Recruit, Execute, Settle, Feedback) for dynamic task allocation, supported by robust fault tolerance and a multidimensional reputation system. Economic incentives are governed by the native ISEKtoken,facilitatingmicropayments,governanceparticipation,andreputationtracking,whileagentsovereigntyismaintainedthroughNFT−basedidentitymanagement.Thissynthesisofblockchaintechnology,artificialintelligence,andincentiveengineeringcreatesaninfrastructurethatactivelyfacilitatesemergentintelligence.ISEKrepresentsaparadigmshiftfromconventionalplatforms,enablingtheorganicdevelopmentoflarge−scale,decentralizedcognitivesystemswhereautonomousagentscollectivelyevolvebeyondcentralizedconstraints.