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Markerless Tracking-Based Registration for Medical Image Motion Correction

13 March 2025
Luisa Neubig
Deirdre Larsen
T. Ikuma
Markus Kopp
Melda Kunduk
Andreas M. Kist
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Abstract

Our study focuses on isolating swallowing dynamics from interfering patient motion in videofluoroscopy, an X-ray technique that records patients swallowing a radiopaque bolus. These recordings capture multiple motion sources, including head movement, anatomical displacements, and bolus transit. To enable precise analysis of swallowing physiology, we aim to eliminate distracting motion, particularly head movement, while preserving essential swallowing-related dynamics. Optical flow methods fail due to artifacts like flickering and instability, making them unreliable for distinguishing different motion groups. We evaluated markerless tracking approaches (CoTracker, PIPs++, TAP-Net) and quantified tracking accuracy in key medical regions of interest. Our findings show that even sparse tracking points generate morphing displacement fields that outperform leading registration methods such as ANTs, LDDMM, and VoxelMorph. To compare all approaches, we assessed performance using MSE and SSIM metrics post-registration. We introduce a novel motion correction pipeline that effectively removes disruptive motion while preserving swallowing dynamics and surpassing competitive registration techniques.

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@article{neubig2025_2503.10260,
  title={ Markerless Tracking-Based Registration for Medical Image Motion Correction },
  author={ Luisa Neubig and Deirdre Larsen and Takeshi Ikuma and Markus Kopp and Melda Kunduk and Andreas M. Kist },
  journal={arXiv preprint arXiv:2503.10260},
  year={ 2025 }
}
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