Using Graph Convolutional Networks to Address fMRI Small Data Problems

Although great advances in the analysis of neuroimaging data have been made, a major challenge is a lack of training data. This is less problematic in tasks such as diagnosis, where much data exists, but particularly prevalent in harder problems such as predicting treatment responses (prognosis), where data is focused and hence limited. Here, we address the learning from small data problems for medical imaging using graph neural networks. This is particularly challenging as the information about the patients is themselves graphs (regions of interest connectivity graphs). We show how a spectral representation of the connectivity data allows for efficient propagation that can yield approximately 12\% improvement over traditional deep learning methods using the exact same data. We show that our method's superior performance is due to a data smoothing result that can be measured by closing the number of triangle inequalities and thereby satisfying transitivity.

@article{screven2025_2502.17489,
  title={ Using Graph Convolutional Networks to Address fMRI Small Data Problems },
  author={ Thomas Screven and Andras Necz and Jason Smucny and Ian Davidson },
  journal={arXiv preprint arXiv:2502.17489},
  year={ 2025 }
}