Electronic-photonic integrated circuits (EPICs) offer transformative potential for next-generation high-performance AI but require interdisciplinary advances across devices, circuits, architecture, and design automation. The complexity of hybrid systems makes it challenging even for domain experts to understand distinct behaviors and interactions across design stack. The lack of a flexible, accurate, fast, and easy-to-use EPIC AI system simulation framework significantly limits the exploration of hardware innovations and system evaluations on common benchmarks. To address this gap, we propose SimPhony, a cross-layer modeling and simulation framework for heterogeneous electronic-photonic AI systems. SimPhony offers a platform that enables (1) generic, extensible hardware topology representation that supports heterogeneous multi-core architectures with diverse photonic tensor core designs; (2) optics-specific dataflow modeling with unique multi-dimensional parallelism and reuse beyond spatial/temporal dimensions; (3) data-aware energy modeling with realistic device responses, layout-aware area estimation, link budget analysis, and bandwidth-adaptive memory modeling; and (4) seamless integration with model training framework for hardware/software co-simulation. By providing a unified, versatile, and high-fidelity simulation platform, SimPhony enables researchers to innovate and evaluate EPIC AI hardware across multiple domains, facilitating the next leap in emerging AI hardware. We open-source our codes at https://github.com/ScopeX-ASU/SimPhony
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