As a prominent challenge in addressing real-world issues within a dynamic environment, label shift, which refers to the learning setting where the source (training) and target (testing) label distributions do not match, has recently received increasing attention. Existing label shift methods solely use unlabeled target samples to estimate the target label distribution, and do not involve them during the classifier training, resulting in suboptimal utilization of available information. One common solution is to directly blend the source and target distributions during the training of the target classifier. However, we illustrate the theoretical deviation and limitations of the direct distribution mixture in the label shift setting. To tackle this crucial yet unexplored issue, we introduce the concept of aligned distribution mixture, showcasing its theoretical optimality and generalization error bounds. By incorporating insights from generalization theory, we propose an innovative label shift framework named as Aligned Distribution Mixture (ADM). Within this framework, we enhance four typical label shift methods by introducing modifications to the classifier training process. Furthermore, we also propose a one-step approach that incorporates a pioneering coupling weight estimation strategy. Considering the distinctiveness of the proposed one-step approach, we develop an efficient bi-level optimization strategy. Experimental results demonstrate the effectiveness of our approaches, together with their effectiveness in COVID-19 diagnosis applications.
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