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ORGANA: A Robotic Assistant for Automated Chemistry Experimentation and Characterization

8 January 2025
Kourosh Darvish
Marta Skreta
Yuchi Zhao
Naruki Yoshikawa
Sagnik Som
Miroslav Bogdanovic
Yang Cao
Han Hao
Haoping Xu
Alán Aspuru-Guzik
Animesh Garg
Florian Shkurti
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Abstract

Chemistry experiments can be resource- and labor-intensive, often requiring manual tasks like polishing electrodes in electrochemistry. Traditional lab automation infrastructure faces challenges adapting to new experiments. To address this, we introduce ORGANA, an assistive robotic system that automates diverse chemistry experiments using decision-making and perception tools. It makes decisions with chemists in the loop to control robots and lab devices. ORGANA interacts with chemists using Large Language Models (LLMs) to derive experiment goals, handle disambiguation, and provide experiment logs. ORGANA plans and executes complex tasks with visual feedback, while supporting scheduling and parallel task execution. We demonstrate ORGANA's capabilities in solubility, pH measurement, recrystallization, and electrochemistry experiments. In electrochemistry, it executes a 19-step plan in parallel to characterize quinone derivatives for flow batteries. Our user study shows ORGANA reduces frustration and physical demand by over 50%, with users saving an average of 80.3% of their time when using it.

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