Chest X-ray (CXR) images are commonly compressed to a lower resolution and bit depth to reduce their size, potentially altering subtle diagnostic features. Radiologists use windowing operations to enhance image contrast, but the impact of such operations on CXR classification performance is unclear. In this study, we show that windowing can improve CXR classification performance, and propose WindowNet, a model that learns optimal window settings. We first investigate the impact of bit-depth on classification performance and find that a higher bit-depth (12-bit) leads to improved performance. We then evaluate different windowing settings and show that training with a distinct window generally improves pathology-wise classification performance. Finally, we propose and evaluate WindowNet, a model that learns optimal window settings, and show that it significantly improves performance compared to the baseline model without windowing.
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