Existing self-supervised learning methods based on contrastive learning and masked image modeling have demonstrated impressive performances. However, current masked image modeling methods are mainly utilized in natural images, and their applications in medical images are relatively lacking. Besides, their fixed high masking strategy limits the upper bound of conditional mutual information, and the gradient noise is considerable, making less the learned representation information. Motivated by these limitations, in this paper, we propose masked patches selection and adaptive masking strategy based self-supervised medical image segmentation method, named MPS-AMS. We leverage the masked patches selection strategy to choose masked patches with lesions to obtain more lesion representation information, and the adaptive masking strategy is utilized to help learn more mutual information and improve performance further. Extensive experiments on three public medical image segmentation datasets (BUSI, Hecktor, and Brats2018) show that our proposed method greatly outperforms the state-of-the-art self-supervised baselines.
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