The segmentation of medical images is a fundamental step in automated clinical decision support systems. Existing medical image segmentation methods based on supervised deep learning, however, remain problematic because of their reliance on large amounts of labelled training data. Although medical imaging data repositories continue to expand, there has not been a commensurate increase in the amount of annotated data. Hence, we propose a new spatial guided self-supervised clustering network (SGSCN) for medical image segmentation, where we introduce multiple loss functions designed to aid in grouping image pixels that are spatially connected and have similar feature representations. It iteratively learns feature representations and clustering assignment of each pixel in an end-to-end fashion from a single image. We also propose a context-based consistency loss that better delineates the shape and boundaries of image regions. It enforces all the pixels belonging to a cluster to be spatially close to the cluster centre. We evaluated our method on 2 public medical image datasets and compared it to existing conventional and self-supervised clustering methods. Experimental results show that our method was most accurate for medical image segmentation.
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