Deep Learning sets the state-of-the-art in many challenging tasks showing outstanding performance in a broad range of applications. Despite its success, it still lacks robustness hindering its adoption in medical applications. Modeling uncertainty, through Bayesian Inference and Monte-Carlo dropout, has been successfully introduced for better understanding the underlying deep learning models. Yet, another important source of uncertainty, coming from the inter-observer variability, has not been thoroughly addressed in the literature. In this paper, we introduce labels uncertainty which better suits medical applications and show that modeling such uncertainty together with epistemic uncertainty is of high interest for quality control and referral systems.
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