In this article, we study the fluctuations of the random variable: {\mathcal I}_n(\rho) = \frac 1N \log\det(\Sigma_n \Sigma_n^* + \rho I_N),\quad (\rho>0) where , as the dimensions of the matrices go to infinity at the same pace. Matrices and are respectively random and deterministic matrices; matrices and are deterministic and diagonal, with respective dimensions and ; matrix has centered, independent and identically distributed entries with unit variance, either real or complex. We prove that when centered and properly rescaled, the random variable satisfies a Central Limit Theorem and has a Gaussian limit. The variance of depends on the moment of the variables and also on its fourth cumulant . The main motivation comes from the field of wireless communications, where represents the mutual information of a multiple antenna radio channel. This article closely follows the companion article "A CLT for Information-theoretic statistics of Gram random matrices with a given variance profile", {\em Ann. Appl. Probab. (2008)} by Hachem et al., however the study of the fluctuations associated to non-centered large random matrices raises specific issues, which are addressed here.
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